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At 24 hours the plasma levels of sildenafil were still somewhere around 200 ng/mL, as compared to roughly 5 ng/mL when sildenafil was dosed alone. This can be in line with ritonavir's marked results with a wide range of P450 substrates. VIAGRA experienced no effect on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS].